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. 2022 Oct 11;50(8):1110–1124. doi: 10.1002/jcu.23265

FIGURE 5.

FIGURE 5

Pathophysiology of CRS‐5. Interaction between systemic disease, heart and kidney in cardiorenal syndrome type 5. DIC, disseminated intravascular coagulation; LPS, lipopolysaccharide; RAAS, renin‐angiotensin‐aldosterone system; ROS, reactive oxygen species; SNS, sympathetic nervous system; SVR, system vascular resistance