TABLE 3.
Comparison of fatigue severity, anxiety, and depression scores (means) between the two cohorts and the general population
| MFS | General population | t | p | Cohen's d | |
|---|---|---|---|---|---|
| n = 155 | CIS n = 1923 | ||||
| HADS n = 199 | |||||
| CIS fatigue | 31.9 ± 8.0 | 23.0 ± 10.8 | 8.586 | <0.0001 | 0.92 |
| HADS anxiety | 5.1 ± 3.6 | 5.1 ± 3.6 | 0.000 | 1.000 | 0 |
| HADS depression | 3.7 ± 3.5 | 3.4 ± 3.3 | 0.826 | 0.288 | 0.09 |
| AMC cohort | General population | t | p | Cohen's d | |
|---|---|---|---|---|---|
| n = 95 | CIS n = 1923 | ||||
| HADS n = 199 | |||||
| CIS fatigue | 32.3 ± 5.0 | 23.0 ± 10.8 | 7.989 | <0.0001 | 1.00 |
| HADS anxiety | 5.4 ± 4.0 | 5.1 ± 3.6 | 0.644 | 0.467 | 0.08 |
| HADS depression | 4.3 ± 3.9 | 3.4 ± 3.3 | 2.059 | 0.027 | 0.26 |
| RESVcue cohort | General population | t | p | Cohen's d | |
|---|---|---|---|---|---|
| n = 60 | CIS n = 1923 | ||||
| HADS n = 199 | |||||
| CIS fatigue | 31.0 ± 11.2 | 23.0 ± 10.8 | 4.986 | <0.0001 | 0.73 |
| HADS anxiety | 4.7 ± 3.2 | 5.1 ± 3.6 | 0.773 | 0.337 | 0.11 |
| HADS depression | 2.8 ± 2.6 | 3.4 ± 3.3 | 1.292 | 0.079 | 0.19 |
Note: Plus‐minus values are means ± SD.
Abbreviations: CIS, checklist individual strength; HADS, hospital anxiety and depression scale; MFS, Marfan syndrome.