TABLE 6.

Factors associated with high levels of anxiety (HADS anxiety subscale ≥8), indicative of an anxiety disorder

	Anxiety ≥8	Univariate			Multivariate
Total n = 155	30 (19%)	OR	CI (95%)	p	OR	CI (95%)	p
Sociodemographic characteristics
Age at inclusion, years	38 (31–50)	0.994	0.960–1.029	0.717	0.987	0.950–1.025	0.485
Gender, male	12 (40%)	1.503	0.625–3.467	0.339	0.806	0.312–2.086	0.657
Marital status, together	19 (63%)	1.072	0.437–2.628	0.880	1.275	0.485–3.350	0.622
Employment, working	20 (67%)	0.532	0.216–1.306	0.168	0.908	0.320–2.575	0.856
Clinical characteristics of MFS
Positive family history	16 (53%)	1.477	0.643–3.394	0.358	1.688	0.693–4.113	0.249
Aortic dilatation	17 (57%)	0.953	0.410–2.213	0.910	1.272	0.510–3.171	0.606
Aortic operation in history	22 (73%)	2.095	0.819–5.363	0.123	1.957	0.712–5.383	0.193
Aortic dissection in history	4 (13%)	0.840	0.257–2.742	0.773	0.467	0.124–1.768	0.262
Chronic pain	12 (40%)	3.706	1.489–9.226	0.005*	3.059	1.175–7.965	0.022*
Skeletal involvement	16 (53%)	2.063	0.904–4.708	0.085**	1.490	0.589–3.767	0.399
Scoliosis	9 (30%)	2.277	0.884–5.864	0.088**	1.714	0.609–4.890	0.305

Abbreviations: CI (95%), 95% confidence interval; OR, odds ratio.

^* p < 0.05 according to the logistic regression analyses, indicating a significant result.

^** p < 0.2 according to the logistic regression analyses, indicating a possible trend.