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. 2022 Oct 2;217(8):424–433. doi: 10.5694/mja2.51722
Guidelines Recommendations Men at increased risk Not recommended
Prostate Cancer Foundation Australia Well informed men aged 50–69 years From age 45 years for men with 2.5–3 times increased risk (eg, a brother diagnosed, particularly if diagnosed at age < 60 years), or age 40 years for those with nine to ten times increased risk (eg, father and two brothers diagnosed) Men aged > 70 years or those with a life expectancy < 15 years
European Association of Urology Well informed men aged ≥ 50 years From age 45 years for men with family history of prostate cancer or men of African descent, and from age 40 years for men carrying BRCA2 mutations Men ≥ 70 years or those with a life expectancy < 15 years
American Urological Association Well informed men aged 55–69 years For men younger than 55 years at higher risk (African American, family history of metastatic prostate cancer, genetic mutations) screening should be individualised Men < 40 years, men > 70, or those with < 10–15‐year life expectancy
National Comprehensive Cancer Network Men aged 55–69 years From age 45–75 years for average risk patients, and from age 40–75 years for African American patients or those with germline mutations Men aged < 40 years, men > 70 years, or those with < 10–15‐year life expectancy