TABLE 3.
Comparison of two different methods for the basophil activation test performed in the KCL laboratory (n = 102). Basophil activation test: mechanisms and considerations for use in clinical trials and clinical practice
| BAT Parameters | IH‐BAT | BC‐BAT | Comparison of 2 BAT methods | ||
|---|---|---|---|---|---|
| Wilcoxon Test | Spearman correlation | Bland–Altman | |||
| %CD63 @10 ng/ml | 10.2 (0.4; 49.2) | 5.0 (0.4; 33.0) | p = .316 |
R s = .835 p < .001 |
B = −0.140 ± 11.16 |
| %CD63 @100 ng/ml | 14.6 (0.9; 56.7) | 6.6 (1.3; 37.2) | p = .077 |
R s = .779 p < .001 |
B = −3.020 ± 19.36 |
| SI CD203c @10 ng/ml | 2.1 (1.2; 5.1) | 1.3 (1.0;2.0) | p < .001 |
R s = .809 p < 0.001 |
B = 1.40 ± 1.783 |
| SI CD203c @100 ng/ml | 2.4 (1.2; 5.5) | 1.3 (1.1; 2.3) | p < .001 |
R s = 0.790 p < 0.001 |
B = 1.323 ± 1.771 |
| Number of basophils @10 ng/ml | 1526 (931; 1958) | 836 (513; 1147) | p < .001 |
R s = .753 p < .001 |
B = 610.8 ± 393.9 |
| Number of basophils @100 ng/ml | 1546 (865; 1936) | 802 (513; 1164) | p < .001 |
R s = .674 p < 0.001 |
B = 623.7 ± 427.9 |
| % Basophils @10 ng/ml | 0.32 (0.23; 0.45) | 0.32 (0.21; 0.44) | p < .001 |
R s = .825 p < .001 |
B = 0.069 ± 0.121 |
| % Basophils @100 ng/ml | 0.33 (0.22; 0.47) | 0.31 (0.20; 0.43) | p < .001 |
R s = .823 p < .001 |
B = 0.082 ± 0.123 |
The bold values indicates p < .05.