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Analysis of the requirement of Y and K in CRD for SMO cholesterylation
(A) Illustration of lysine (K, magenta) and tyrosine (Y, green) residues in the SMO-CRD structure based on PDB: 5L7D. The Y85 and K133 residues are enlarged on the right. (B–E) Cholesterylation of SMO variants. The experiments were done as described in Figure1B.
