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Overexpression of cyclin B1 can rescue the PTBP1-knockdown phenotype in ESCC cells
(A) Transwell migration and invasion assays. After knockdown of PTBP1, cyclin B1 was overexpressed in the ESCC cells. KYSE 30 cells were used for the transwell migration and invasion assays as previously described. (B) In vivo tumorigenesis assay. A total of 1×106 KYSE 30 cells were injected into the flank of nude mice by intraperitoneal injection. Tumors were harvested 30 days after injection. n=5.
