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. 2022 Sep 20;54(9):1234–1243. doi: 10.3724/abbs.2022124

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© The Author(s) 2021.

This is an open access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0/).

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NAP1L1 is upregulated in colon cancer and is an unfavorable factor

(A) Analysis of The Cancer Genome Atlas database suggests that NAP1L1 is upregulated in colorectal cancer ( P=1.6×10 –12). (B) Analysis of the Clinical Proteomic Tumor Analysis Consortium database analysis suggests that NAP1L1 protein level is upregulated in colorectal cancer ( P=1.5×10 –26). (C) Immunohistochemistry analyses using tissue microarray chips were performed to detect NAP1L1 protein expression in colon cancer tissues and adjacent tissues in early- and late-stage colon cancer. Scale bar: 200 μm. (D) A Kaplan-Meier survival analysis of the overall survival of 101 patients with colon cancer was performed based on NAP1L1 expression levels ( P=0.01). The log-rank test was used to calculate P-values.