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. 2023 Jan 9;13:442. doi: 10.1038/s41598-022-27342-0

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Desaturation definition and parameters. (a) Hypoxic burden for each relative or absolute desaturation definition (see supplementary information and Figure S2). The hypoxic burden was defined as the sum of desaturation areas normalised by recording duration. The hypoxic burden was based on relative or absolute threshold and was measured under oxygen support, mechanical ventilation or without support in critical and non-critical patients. (b) Desaturation characteristics for critical and non-critical patients with or without oxygen or mechanical support. The results are shown for an absolute desaturation threshold of 93%. The number of desaturations per hour, the depth the area and the desaturation time (duration between the beginning and the minimum) are represented for each group. *** Wilcoxon test p value < 0.001,** p value < 0.01,* p value < 0.05, NS non-significant. The center of boxplot indicates the median, and the low and high edges indicate the 25th and 75th percentiles, points indicate outliers.