TABLE 1.
Clinical characteristics of enrolled patients with extranodal NK/T‐cell lymphoma, nasal‐type (n = 742)
| Primary cohort | Validation cohort | |
|---|---|---|
| Characteristics | No. (%) | No. (%) |
| All | 186 | 556 |
| Sex | ||
| Male | 140 (75.3) | 391 (70.3) |
| Female | 46 (24.7) | 165 (29.7) |
| Age, y | ||
| ≤60 | 153 (82.3) | 472 (84.9) |
| >60 | 33 (17.7) | 84 (15.1) |
| Primary site | ||
| UADT | 143 (76.9) | 489 (87.9) |
| Extra‐UADT | 43 (23.1) | 67 (12.1) |
| Regional lymph nodes | ||
| Yes | 73 (39.2) | 271 (48.7) |
| No | 113 (60.8) | 285 (51.3) |
| Distant lymph nodes | ||
| Yes | 51 (27.4) | 52 (9.4) |
| No | 135 (72.6) | 504 (90.6) |
| B symptoms | ||
| Yes | 120 (64.5) | 186 (33.5) |
| No | 66 (35.5) | 370 (66.5) |
| Elevated LDH | ||
| Yes | 101 (54.3) | 187 (33.6) |
| No | 85 (45.7) | 369 (66.4) |
| ECOG score | ||
| 0‐1 | 140 (75.3) | 548 (98.5) |
| ≥2 | 46 (24.7) | 8 (1.5) |
| Ann Arbor stage | ||
| I‐II | 100 (53.8) | 423 (76.1) |
| III‐IV | 86 (46.2) | 133 (23.9) |
| Bone marrow aspiration | ||
| Negative | 156 (83.9) | 547 (98.4) |
| Positive | 30 (16.1) | 9 (1.6) |
| Bone marrow biopsy | ||
| Negative | 141 (75.8) | 534 (96.0) |
| Positive | 45 (24.2) | 22 (4.0) |
| PET/CT | ||
| Yes | 139 (74.7) | 425 (76.4) |
| No | 47 (25.3) | 131 (23.6) |
Abbreviations: CT, computed tomography; ECOG, Eastern Cooperative Oncology Group; LDH, lactate dehydrogenase; PET, positron emission tomography; UADT, upper aerodigestive tract.