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. 2023 Jan 5;61(1):165–176. doi: 10.1080/13880209.2022.2160770

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© 2023 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 4. — Luteolin reduces the secretion of IL-36γ and IL-1β in Beas-2B cells and inhibits the activation of mitogen-activated protein kinase (MAPK) pathways under lipopolysaccharide (LPS) stimulation. (A–D) IL-1β, p-p38, p38, p-REK, ERK, p-JNK and JNK in Beas-2B cells under LPS stimulation as detected by western blot. (E) IL-36γ in Beas-2B cells under LPS stimulation as detected by enzyme-linked immunosorbent assay (ELISA). (F–I) Protein intensity analysis of IL-1β, p-p38, p38, p-REK, ERK, p-JNK and JNK in Beas-2B cells under LPS stimulation as detected by western blotting. *p< 0.05 versus the control group. ^#p< 0.05 versus the LPS group.