Figure 4.

Global dynamics and DD modulation functional description. (a) Heatmap/hierarchical clustering using Mercator4 categorization terms. The numbers indicate scaled expression, by rows, according to the Mercator4 functional bin. Relevant terms are highlighted. (b) Volcano analysis of DD event isoforms. Not significant, FDR‐adjusted P > 0.05 and absolute log₂(fold change) < 1.8; Significant, FDR‐adjusted P < 0.05 and absolute log₂(fold change) < 1.8; Fold Change, FDR‐adjusted P > 0.05 and absolute log₂(fold change) > 1.8; Significant & Fold Change, FDR‐adjusted P < 0.05 and absolute log₂(fold change) > 1.8. (c) Gene set enrichment analysis of DD event isoforms using Mercator4 functional categories. Blue and gold indicate significantly and non‐significantly enriched terms, respectively. The sampling times correspond to the 40°C assay shown in Figure 1.