TABLE 2.

Caregiver quality of life, caregiving burden, and treatment-related distress over time

	Part I		Part II
	Baseline (n = 96)		Day 90 (n = 53)		Day 180 (n = 49)
	Mean	99% CI	Mean	99% CI	Mean	99% CI
Quality of life
Physical function	51.32	49.00–53.64	50.35	47.22–53.49	50.57	47.54–53.60
Pain	61.32	57.98–64.66	59.35	54.65–64.04	52.77	48.33–57.22
Fatigue	49.11	46.80–51.42	49.71	45.35–54.06	48.91	44.15–53.67
Anxiety	51.53	49.23–53.82	54.01	48.57–59.45	59.93	54.11–65.75
Depression	48.68	46.70–50.66	48.91	45.33–52.50	49.24	45.30–53.17
Caregiving burden	22.65	18.76–26.55	21.61	15.23–27.99	20.41	13.96–26.85
Distress	-	-	11.81	8.17–15.46	11.63	7.40–15.86

Notes: Higher scores indicate more of all variables assessed. Treatment-related distress was not assessed in Part I of the study because CAR T-cell therapy had not yet occurred. Bold numbers indicate statistically significant differences among outcomes over time.