Table II.

Association of biomarkers and death or severe brain injury by MRI (NICHD score ≥2B)

Timepoints	N babies	Unadjusted				Adjusted*
		OR	95% CI		P	aOR	95% CI		P
			Lower	Upper			Lower	Upper
Log GFAP
Day 0	48	1.00	0.98	1.01	.539	0.99	0.98	1.00	.269
Day 1	50	1.00	0.98	1.01	.567	0.99	0.98	1.01	.287
Day 2	51	1.00	0.98	1.01	.648	1.00	0.98	1.02	.857
Day 3	45	1.00	0.98	1.01	.401	0.99	0.98	1.00	.253
Day 4	50	1.00	0.98	1.01	.474	0.99	0.98	1.00	.219
Log NRGN
Day 0	48	0.98	0.87	1.09	.670	0.93	0.84	1.03	.175
Day 1	50	0.98	0.89	1.07	.627	0.94	0.86	1.03	.182
Day 2	51	0.97	0.86	1.10	.640	1.02	0.91	1.15	.693
Day 3	45	0.97	0.91	1.04	.464	0.96	0.90	1.03	.238
Day 4	50	0.97	0.88	1.08	.609	0.94	0.86	1.04	.235
Log Tau
Day 0	46	1.00	0.98	1.02	.780	0.99	0.97	1.01	.266
Day 1	49	1.00	0.98	1.02	.827	0.99	0.97	1.01	.278
Day 2	51	1.07	1.04	1.10	.000	1.06	1.03	1.09	.001
Day 3	45	1.04	1.02	1.06	.000	1.04	1.01	1.06	.007
Day 4	50	1.02	1.00	1.03	.011	1.01	1.00	1.03	.156

Bolded values denote statistical significance.

^*Adjusted for baseline encephalopathy (Sarnat score) and site.