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. 2022 Dec 27;18(12):e1010548. doi: 10.1371/journal.pgen.1010548

Fig 2. Expression of IgG2a and IgG2c by founder strain haplotype at the heavy chain locus.

Fig 2

The mean value for IgG2a and IgG2c concentration (ug/mL) was determine for each CC strain. Mean values were plotted by the founder strain haplotype at the immunoglobulin heavy chain locus (Chromosome 12: 113 – 120Mb). Black bars indicate the mean concentration for a given founder haplotype and each individual point represents a strain with that founder haplotype at Igh. The y-axis is the concentration for IgG2a or IgG2c in ug/mL and the x-axis is the founder strain haplotype groups. Strains with undetectable concentrations of IgG2a or IgG2c were set to the lower limit of detection of the assay. Limit of detection represented by the dashed black line.