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. 2022 Dec 21;3(1):4. doi: 10.3892/mi.2022.64

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Copyright: © Kubota et al.

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ) and either DOI or URL of the article must be cited.

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Comparison of serum TSTD2 antibody levels in HDs, and patients with type-1, -2 and -3 CKD. (A) Serum TSTD2 antibody levels were quantified using amplified luminescence proximity homogeneous assay-linked immunosorbent assay and compared between the HD group and the type-1 (diabetic kidney disease), type-2 (nephrosclerosis) and type-3 (glomerulonephritis) CKD subgroups. TSTD2 antibody levels are depicted in a box-whisker plot. (B and C) The TSTD2 antibody levels were analyzed using a ROC curve to compare type-1 and type-2 CKDs. The numbers in the graphs indicate the AUC, specificity, sensitivity and cutoff values. TSTD2, thiosulfate sulfurtransferase-like domain-containing 2; CKD, chronic kidney disease; ROC, receiver operating characteristic; AUC, area under the curve.