Table 1.
The primary data information that is extracted from the incorporated articles.
| SNPs | First Author | yr | Country | Ethnicity | Control source | Cancer type | Case | Control | HWE (P) | Genotyping method | NOS |
|---|---|---|---|---|---|---|---|---|---|---|---|
| rs4939827 | CC/TC/TT | CC/TC/TT | |||||||||
| (T > C) | Broderick | ||||||||||
| -A group | 2007 | UK | Caucasian | NA | colon | 153/449/328 | 229/480/251 | 0.987 | Illumina | 7 | |
| -B group | 2007 | UK | Caucasian | NA | colon | 852/2178/1392 | 845/1915/1084 | 0.989 | Allele-PCR | 7 | |
| -C group | 2007 | UK | Caucasian | NA | colon | 387/982/623 | 410/840/430 | 0.995 | Allele-PCR | 7 | |
| -D group | 2007 | UK | Caucasian | NA | colon | 194/477/292 | 76/171/96 | 0.993 | Allele-PCR | 7 | |
| Tenesa | |||||||||||
| Scotland | 2008 | Scotland | Caucasian | NA | colon | 538/1521/926 | 706/1508/845 | 0.506 | Illumina | 7 | |
| -Japan | 2008 | Japan | Asian | NA | colon | 233/1582/2576 | 131/1028/2019 | 0.992 | TaqMan | 7 | |
| -Canada | 2008 | Canada | Caucasian | NA | colon | 225/593/355 | 284/576/322 | 0.402 | TaqMan | 7 | |
| -England | 2008 | England | Caucasian | NA | colon | 418/1120/694 | 546/1126/578 | 0.959 | TaqMan | 7 | |
| -Spain | 2008 | Spain | Caucasian | NA | colon | 62/156/131 | 57/143/95 | 0.808 | TaqMan | 7 | |
| -Scotland | 2008 | Scotland | Caucasian | NA | colon | 156/420/254 | 189/446/288 | 0.497 | TaqMan | 7 | |
| -Israel | 2008 | Israel | Caucasian | NA | colon | 267/638/447 | 312/627/397 | 0.035 | TaqMan | 7 | |
| -Germany | 2008 | Germany | Caucasian | NA | colon | 420/1071/659 | 541/1057/530 | 0.762 | TaqMan | 7 | |
| -Germany | 2008 | Germany | Caucasian | NA | colon | 289/617/412 | 378/704/358 | 0.403 | TaqMan | 7 | |
| Curtin | 2009 | Multi | Caucasian | PB | colon | 221/520/324 | 229/538/274 | 0.251 | SNPlex | 8 | |
| Thompson | 2009 | US | Mixed | PB | colon | 125/275/154 | 146/378/185 | 0.064 | TaqMan | 7 | |
| Pittman | 2009 | UK | Caucasian | HB | colon | 785/1250/497 | 725/1300/582 | 0.987 | Mixed | 7 | |
| Slattery | 2010 | US | Caucasian | Mixed | colon | 360/773/457 | 492/992/503 | 0.947 | TaqMan | 7 | |
| Xiong | 2010 | China | Asian | PB | colon | 1370/677/77 | 1442/570/74 | 0.060 | PCR-RFLP | 8 | |
| von Hoslt | 2010 | Sweden | Caucasian | HB | colon | 395/886/501 | 387/884/408 | 0.029 | TaqMan | 8 | |
| Kupfer | 2010 | US | African | HB | colon | 379/340/76 | 455/429/101 | 0.993 | MassARRAY | 7 | |
| 2010 | US | Caucasian | HB | colon | 88/199/112 | 85/183/99 | 0.981 | MassARRAY | 7 | ||
| Mates | 2010 | Rome | Caucasian | PB | colon | 28/37/27 | 15/57/23 | 0.042 | Centaurus | 6 | |
| Mates | 2011 | Rome | Caucasian | PB | colon | 42/69/42 | 32/106/43 | 0.018 | Centaurus | 6 | |
| Cui | 2011 | Japan | Asian | PB | colon | 1628/1007/155 | 2247/1190/147 | 0.501 | Illumina | 8 | |
| Li | 2011 | China | Asian | PB | colon | 73/53/12 | 81/73/14 | 0.665 | MassARRAY | 8 | |
| Ho | 2011 | China | Asian | HB | colon | 343/420/129 | 376/405/109 | 0.997 | MassARRAY | 7 | |
| Song | 2012 | China | Asian | HB | colon | 399/232/10 | 732/272/33 | 0.214 | TaqMan | 7 | |
| Lubbe | 2012 | UK | Caucasian | HB | colon | 444/969/624 | 1394/3021/1636 | 0.993 | Allele-PCR | 7 | |
| Garcia-Albeniz | 2012 | US | Caucasian | HB | colon | 90/233/118 | 538/1120/600 | 0.731 | TaqMan | 7 | |
| Phipps | 2012 | US | Caucasian | HB | colon | 657/1526/884 | 574/1597/1112 | 0.988 | Illumina | 7 | |
| Kirac | 2013 | Croatia | Caucasian | PB | colon | 63/143/96 | 172/291/131 | 0.705 | TaqMan | 8 | |
| Yang | 2014 | China | Asian | PB | colon | 342/298/65 | 891/752/159 | 0.985 | MassARRAY | 7 | |
| Kurlapska | 2014 | Poland | Caucasian | PB | colon | 54/93/65 | 716/1394/730 | 0.330 | TaqMan | 7 | |
| Zhang | 2014 | MC | Asian | PB | colon | 400/277/51 | 1894/1170/212 | 0.086 | Mixed | 7 | |
| Hong | 2015 | Korea | Asian | PB | colon | 126/63/9 | 182/127/19 | 0.608 | Illumina | 7 | |
| Baert-Desurmont | 2016 | French | Caucasian | HB | colon | 89/157/104 | 191/493/343 | 0.555 | snapshot | 7 | |
| Abd EI-Fattah | 2016 | Egypt | Caucasian | NA | colon | 20/35/22 | 11/15/10 | 0.319 | TaqMan | 7 | |
| Alonso-Molero | 2017 | MC | Caucasian | PB | colon | 176/524/387 | 495/1185/729 | 0.738 | Illumina | 7 | |
| Shaker | 2018 | Egypt | Caucasian | HB | colon | 13/44/29 | 13/15/8 | 0.367 | Taq Man | 7 | |
| Reilly | 2021 | MC | Caucasian | HB | colon | 9/16/5 | 9/37/14 | 0.061 | Amplifluor | 6 | |
| Alidoust | 2022 | Iran | Caucasian | NA | colon | 89/83/37 | 78/101/16 | 0.330 | ARMS | 7 | |
| rs4464148 | TT/TC/CC | TT/TC/CC | |||||||||
| (T > C) | Broderick | ||||||||||
| -A group | 2007 | UK | Caucasian | NA | colon | 389/425/116 | 486/394/80 | 0.991 | Illumina | 7 | |
| -B group | 2007 | UK | Caucasian | NA | colon | 2017/1952/472 | 1886/1617/346 | 0.982 | Allele-PCR | 7 | |
| -C group | 2007 | UK | Caucasian | NA | colon | 922/845/193 | 827/696/146 | 0.980 | Allele-PCR | 7 | |
| -D group | 2007 | UK | Caucasian | NA | colon | 422/408/99 | 171/137/27 | 0.952 | Allele-PCR | 7 | |
| Thompson | 2009 | US | Mixed | PB | colon | 269/231/61 | 342/324/53 | 0.045 | TaqMan | 7 | |
| Curtin | 2009 | US | Caucasian | PB | colon | 503/472/95 | 535/423/89 | 0.678 | SNPlex | 8 | |
| Pittman | 2009 | UK | Caucasian | HB | colon | 1161/1107/264 | 1095/1277/235 | <0.001 | Mixed | 7 | |
| Ho | 2011 | China | Asian | HB | colon | 739/146/7 | 770/116/4 | 0.869 | MassARRAY | 7 | |
| Zhang | 2014 | MC | Asian | PB | colon | 1/52/675 | 14/305/2957 | 0.045 | TaqMan | 7 | |
| Kurlapska | 2014 | Poland | Caucasian | PB | colon | 1214/1228/400 | 84/96/33 | 0.523 | TaqMan | 7 | |
| Damavand | 2015 | Iran | Caucasian | HB | colon | 138/78/37 | 113/101/20 | 0.700 | PCR-RFLP | 7 | |
| Serrano-fernadez | 2015 | MC | Caucasian | PB | colon | 507/517/141 | 561/490/114 | 0.643 | Taqman | 8 | |
| Reilly | 2021 | MC | Caucasian | HB | colon | 10/16/2 | 27/23/5 | 0.974 | Amplifluor | 6 | |
| rs12953717 | CC/TC/TT | CC/TC/TT | |||||||||
| (C > T) | Broderick | ||||||||||
| A group | 2007 | UK | Caucasian | NA | colon | 159/309/151 | 326/467/167 | 0.991 | Illumina | 7 | |
| B group | 2007 | UK | Caucasian | NA | colon | 1247/2204/973 | 1248/1898/722 | 0.994 | Allele-PCR | 7 | |
| C group | 2007 | UK | Caucasian | NA | colon | 582/991/422 | 558/834/312 | 0.990 | Allele-PCR | 7 | |
| D group | 2007 | UK | Caucasian | NA | colon | 277/468/198 | 106/168/67 | 0.976 | Allele-PCR | 7 | |
| Middeldorp | 2009 | Netherlands | Caucasian | HB | colon | 301/493/201 | 482/643/215 | 0.982 | KASPar | 6 | |
| Curtin | 2009 | US | Caucasian | PB | colon | 314/530/226 | 332/521/188 | 0.509 | SNPlex | 8 | |
| Thompson | 2009 | US | Mixed | PB | colon | 196/248/116 | 220/370/129 | 0.218 | TaqMan | 7 | |
| Pittman | 2009 | UK | Caucasian | HB | colon | 716/1261/555 | 859/1275/473 | 0.998 | Mixed | 7 | |
| Kupfer | 2010 | US | African | HB | colon | 401/327/67 | 525/388/72 | 0.979 | MassARRAY | 7 | |
| 2010 | US | Caucasian | HB | colon | 197/121/81 | 119/180/68 | 0.996 | MassARRAY | 7 | ||
| Slattery | 2010 | US | Caucasian | Mixed | colon | 503/754/332 | 676/928/327 | 0.779 | Illumina | 7 | |
| Li | 2011 | China | Asian | PB | colon | 57/79/6 | 90/63/13 | 0.672 | MassARRAY | 8 | |
| Ho | 2011 | China | Asian | HB | colon | 276/343/97 | 304/345/65 | 0.018 | MassARRAY | 7 | |
| Scollen | 2011 | UK | Mixed | NA | colon | 710/1031/425 | 730/1083/437 | 0.326 | TaqMan | 7 | |
| Zhang | 2014 | China | Asian | PB | colon | 418/263/47 | 1947/1135/194 | 0.096 | TaqMan | 7 | |
| Damavand | 2015 | Iran | Caucasian | HB | colon | 78/90/66 | 68/97/88 | <0.001 | PCR-RFLP | 7 | |
| Lu | 2015 | China | Asian | NA | colon | 401/49/127 | 379/37/169 | <0.001 | PCR-RFLP | 6 | |
| Reilly | 2021 | MC | Caucasian | HB | colon | 9/13/8 | 19/30/11 | 0.889 | Amplifluor | 6 |
Bold indicates that the result of HWE is less than 0.05 (n = 10).
HB = hospital based, HWE = Hardy-Weinberg equilibrium, MC = studies in the article were not conducted in the same country or region, mixed (control source) = the control group was derived from both PB and HB, Mixed (ethnicity) = Study subjects belong to two or more races that cannot be grouped together, Multi (country) = multi-center study, NA = the source of the control group was unclear, NOS = The Newcastle-Ottawa scale, PB = population based, SNPs = single nucleotide polymorphisms.