Fig. 1.

Tensor-based morphometric analysis of gray matter tissue without and with the optimal transport feature extraction step. The pink color shows inverse correlation strength of gray matter between patients with mild dementia compared to normal aging controls for voxels with Bonferroni corrected p < 0.05. The optimal transport feature extraction improves the statistical power and shows regions of gray matter tissue loss associated with mild dementia that are not identified with a standard TBM analysis (more details of the analysis are in Section 5).