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Tissue expression heat map of CSPG core proteins (A) and CS/DS biosynthetic enzymes (B). Under the CSPG superfamily umbrella, a number of subfamilies cluster particularly cell surface CSPGs, small leucine-rich PGs, and large extracellular CSPGs found in the extracellular matrix. Data publicly available from the Genotype-Tissue Expression (GTEx) project (V8) (https://www.gtexportal.org). CS/DS, chondroitin sulfate/dermatan sulfate; CSPG, chondroitin sulfate proteoglycan.
