Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Jan 9;6:20. doi: 10.1038/s42003-022-04406-5

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 3 — a PCoA plot visualizing the beta diversity with Bray–Curtis distance in females (n = 24) and males (n = 24) on an HFD treated with vehicle, E2, and DPN. b Boxplots presenting the significance of the beta diversity between corresponding groups (all HFD), with Bray–Curtis distance. c Scatter plots of the microbial rank in males against the microbial rank in females upon treatment with E2 (upper panel) or DPN (lower panel). The lower right corner indicates the top-ranked species in both sexes upon E2 and DPN treatment, respectively. d Volcano plots show a degree of alteration of species by E2 and DPN treatment in both sexes. e Boxplot of the additive-log-ratio transformed taxa showing the significantly altered species by E2 and DPN treatment in both sexes (n = 8 per group). The boxplots are shown as median (line), interquartile range (box), and minimum to maximum data range (whisker). ^**FDR < 0.01 (Benjamini–Hochberg-adjusted).