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. 2023 Jan 5;18:79–94. doi: 10.2147/IJN.S394819

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© 2023 Zou et al.

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Characterization of 6-MPNs in vitro and in vivo. The morphology of 6-MPNs measured by Transmission Electron Microscope (TEM) (A). (B) In vitro release of 6-MP from 6-MPNs and 6-MPCs in PBS containing 0.02% Tween 20. (C) In vivo plasma concentrations (ng/mL) of 6-MP vs Time (h) profiles after a single oral administration of 6-MPNs or 6-MPCs in SD rats.