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. 2023 Jan 4;37:03946320221150720. doi: 10.1177/03946320221150720

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© The Author(s) 2023

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Figure
5. — Photomicrograph of colon mucosa of male rats of; (a) Control group, showing normal histological structure of intestinal mucosa and the intestinal glands appeared intact and lined by high cuboidal epithelial cells score (0) arrow (H&E X200); (b) BAs-ZnNPs group, showing normal histological structure of both villi and gland with numerous numbers of intestinal glands score (0) arrow (H&E X200); (c) DSS group, showing loss of villus architecture with disappearance of inter-villus space and zonal destruction of the epithelial surface and zonal crypt loss score (2) arrow (H&E X200); (d): DSS + BAs group, showing few numbers of inflammatory cells were detected in both mucosa and submucosa score (1) and the intestinal glands showed intact epithelial lining with basal basophilic nuclei. Leukocytic infiltration of lamina propria by mononuclear leukocytes mainly lymphocytes and macrophages was detected score (1). (e): DSS + BA-ZnNPs group, showing epithelial shedding and leukocytic infiltration of lamina propria by mononuclear leukocytes score (1) arrow (H&E X200).