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. 2001 May;69(5):3413–3417. doi: 10.1128/IAI.69.5.3413-3417.2001

FIG. 1.

FIG. 1

Photomicrographs of tissue sections stained with immunoperoxidase for IFN-γ and IL-12 expression in a BT patient (patient 380; BT-RR, 40× objective). (A) IFN-γ staining in a reactional granuloma in a biopsy taken at day 0. (B) A high level of IFN-γ expression is seen and appears unchanged at day 7. (C) Fewer cells are present in a smaller granuloma at day 28, and the level of IFN-γ expression has decreased compared with expression in the day 0 and 7 biopsies. IL-12 is strongly expressed in granulomas in biopsies taken at day 0 (D), and a similar level of positive staining is seen at day 7 (E). (F) The granuloma size and level of positive staining have decreased by day 28.