Table 6.

Sensitivity and Specificity of the Noncardiac Biomarkers in Identifying Myocarditis

	ALT		AST		CPK		LDH
	Sensitivity (95% CI)	Specificity (95% CI)	Sensitivity (95% CI)	Specificity (95% CI)	Sensitivity (95% CI)	Specificity (95% CI)	Sensitivity (95% CI)	Specificity (95% CI)
>ULN	0.94 (0.82-1.00)	0.03 (0.02. 0.03)	0.97 (0.86-1.00)	0.06 (0.05-0.07)	0.99 (0.94-1.00)	0.23 (0.21-0.25)	0.85 (0.62-0.99)	0.11
>2× ULN	0.82 (0.65-1.00)	0.06 (0.05-0.07)	0.95 (0.84-1.00)	0.12 (0.11-0.13)	0.98 (0.90-1.00)	0.23 (0.21-0.25)	0.40 (0.11-0.70)	0.56
>3× ULN	0.71 (0.47-0.94)	0.12 (0.10-0.13)	0.91 (0.72-1.00)	0.35 (0.33-0.36)	0.92 (0.76-0.99)	0.31 (0.28-0.34)	—	—
>4× ULN	0.71 (0.47-0.94)	0.34 (0.32-0.36)	0.71 (0.48-0.94)	0.41 (0.38-0.43)	0.76 (0.56-0.95)	0.54 (0.51-0.57)	—	—

ULN: ALT, 49 IU/L; AST, 34 IU/L; LDH, 240 IU/L; CPK, 240 IU/L. We are unable to calculate the 95%CI for LDH >3 and >4 ULN due to the low sample size for these subgroups.

Abbreviations as in Tables 1 and 5.