Table 2.
Laboratory and Imaging Findings in Patients With Myocarditis at Baseline and Diagnosis
|
Case |
Sex | Age at ICI Start (y) | TnI at Baseline (pg/mL) | Symptoms/Presentation | TnI at Diagnosis (pg/mL) | ECG | Echocardiography | MRI | ESC Criteria of Hermann et al33 |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Male | 36 | 1.4 | Dyspnea Fatigue |
380 | Reduced R-wave height ST-segment elevation in V1-V3 |
Preserved LVEF LV wall thickening |
Definite findings | Pathological diagnosis |
| 2 | Female | 49 | 0.5 | Dyspnea Fatigue Cardiogenic shock |
441 | Reduced R-wave height | Preserved LVEF LV wall thickening |
No signs of myocarditis | Pathological diagnosis |
| 3 | Male | 88 | 89.7 | Dyspnea Fatigue Muscle weakness (Myositis) |
1,374 | Ectopy T-wave inversion |
Reduced LVEF Diffuse hypokinesis LV wall thickening |
Not performed | Troponin elevation 3 minor criteria |
| 4 | Male | 51 | 5.3 | Dizziness | 16.7 | Ectopy | Reduced LVEF Diffuse hypokinesis |
Definite findings | Not applicable (1 major/2 minor) |
| 5 | Male | 65 | 10.1 | Dizziness Fatigue Diplopia (Myositis) |
200 | No change | Preserved LVEF | Not performed | Troponin elevation 2 minor criteria |
| 6 | Male | 73 | 15.5 | Fatigue Muscle weakness (Myositis) |
285 | Reduced R-wave height | Preserved LVEF | Not performed | Troponin elevation 2 minor criteria |
CMR = cardiac magnetic resonance; ECG = electrocardiogram; ESC = European Society of Cardiology; MRI = magnetic resonance imaging; other abbreviations as in Table 1.