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. 2022 Dec;13(6):3100–3111. doi: 10.21037/jgo-22-1215

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2022 Journal of Gastrointestinal Oncology. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

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The protein expressions of p-Src, p-ERK1/2, MMP-2, MMP-3, MMP-9 CyclinD1, and CyclinA2 in SW480 cells measured by western blot. (A) Representative western images of above proteins in cells transfected with the NC RNA of PLAU-inhibitor (PLAU-NC), PLAU-inhibitor, the NC for PLAU-mimic (PLAU-NC), and PLAU-mimic. (B) The relative expression of p-Src, p-ERK1/2, MMP-2, MMP-3, MMP-9, CyclinD1, CyclinA2, and GADPH in each group. **, P<0.01. ns, not significant. PLAU, plasminogen activator, urokinase; NC, negative control; MMP, matrix metallopeptidase.