Table 8. Relationship between CHD4 expression and clinicopathological data of patients.
Variable | Total, n (%) | CHD4 low expression, n (%) | CHD4 high expression, n (%) | P |
---|---|---|---|---|
Gender | 0.520 | |||
Male | 66 (66.0) | 28 (42.4) | 38 (57.6) | |
Female | 34 (34.0) | 17 (50.0) | 17 (50.0) | |
Age (years) | 0.092 | |||
<64 | 55 (55.0) | 24 (43.6) | 31 (56.4) | |
≥64 | 45 (45.0) | 21 (46.7) | 24 (53.3) | |
Loss of body mass (kg) | 0.105 | |||
<5 | 56 (56.0) | 26 (46.4) | 30 (53.6) | |
≥5 | 44 (44.0) | 19 (43.2) | 25 (56.8) | |
CEA (ng/mL) | 3.778 | |||
≤5 | 56 (56.0) | 30 (53.6) | 26 (46.4) | |
>5 | 44 (44.0) | 15 (34.1) | 29 (65.9) | |
Serum albumin (g/L) | 1.010 | |||
<35 | 80 (80.0) | 34 (42.5) | 46 (57.5) | |
≥35 | 20 (20.0) | 11 (55.0) | 9 (45.0) | |
Tumor size (cm) | 5.533 | |||
<3 | 63 (63.0) | 34 (54.0) | 29 (46.0) | |
≥3 | 37 (37.0) | 11 (29.7) | 26 (70.3) | |
Differentiation of tumor | 4.302 | |||
High to middle differentiation | 53 (53.0) | 29 (54.7) | 24 (45.3) | |
Low differentiation | 47 (47.0) | 16 (34.0) | 31 (66.0) | |
Site of tumor | 0.253 | |||
High-medium | 36 (36.0) | 15 (41.7) | 21 (58.3) | |
Low | 64 (64.0) | 30 (46.9) | 34 (53.1) | |
TNM stage | 10.725 | |||
I–II | 32 (32.0) | 22 (68.8) | 10 (31.2) | |
III–IV | 68 (68.0) | 23 (33.8) | 45 (66.2) | |
Depth of infiltration | 0.049 | |||
In the early (Tis + T1) | 21 (21.0) | 9 (42.9) | 12 (57.1) | |
Stage of progression (T2–T4) | 79 (79.0) | 36 (45.6) | 43 (54.4) | |
Chemotherapy | 3.093 | |||
Yes | 64 (64.0) | 33 (51.6) | 31 (48.4) | |
No | 36 (36.0) | 12 (33.3) | 24 (66.7) | |
Distant transfer | 0.088 | |||
Yes | 8 (8.0) | 4 (50.0) | 4 (50.0) | |
No | 92 (92.0) | 41 (44.6) | 51 (55.4) | |
Lymph node metastasis | 0.042 | |||
Yes | 4 (4.0) | 2 (50.0) | 2 (50.0) | |
No | 96 (96.0) | 43 (44.8) | 53 (55.2) | |
Invasion of nerve | 1.584 | |||
Yes | 21 (21.0) | 12 (57.1) | 9 (42.9) | |
No | 79 (79.0) | 33 (41.8) | 46 (58.2) |
CEA, carcinoembryonic antigen; TNM, tumor/lymph nodes/metastasis; CHD4, chromodomain helicase DNA binding protein 4.