Table 1.
Characteristics | Total | Childhood BMI trajectory |
||||
---|---|---|---|---|---|---|
Below average | Average | Above average | Overweight | Obesity | ||
Women | ||||||
No. of women (%) | 149 325 | 31 232 (20.9) | 59 357 (39.8) | 39 974 (26.8) | 15 215 (10.2) | 3547 (2.4) |
Year of birth, median (IQR) | 149 325 | 1951 (1942-1964) | 1949 (1940-1962) | 1949 (1941-1963) | 1952 (1943-1967) | 1961 (1947-1978) |
BMI at age 7 y, median (IQR), kg/m2 | 140 284 | 14.0 (13.6-14.5) | 15.0 (14.6-15.5) | 16.0 (15.5-16.6) | 17.2 (16.5-18.0) | 19.2 (18.1-20.4) |
Height at age 7 y, median (IQR), m | 140 284 | 1.20 (1.17-1.24) | 1.21 (1.18-1.25) | 1.22 (1.19-1.26) | 1.24 (1.20-1.27) | 1.25 (1.22-1.29) |
Obesity-related cancer, No. (%) | 7285 (4.9) | 1360 (4.4) | 2917 (4.9) | 2059 (5.2) | 771 (5.1) | 178 (5.0) |
Premenopausal breast cancer, No. (%)b | 3812 (2.6) | 892 (2.9) | 1547 (2.6) | 1030 (2.6) | 301 (2.0) | 42 (1.2) |
Postmenopausal breast cancer, No. (%)b | 6406 (4.3) | 1477 (4.7) | 2807 (4.7) | 1638 (4.1) | 445 (2.9) | 39 (1.1) |
Type 2 diabetes, No. (%) | 11 696 (7.8) | 1887 (6.0) | 3969 (6.7) | 3412 (8.5) | 1809 (11.9) | 619 (17.5) |
Men | ||||||
No. of men (%) | 152 602 | 35 208 (23.1) | 64 817 (42.5) | 37 990 (24.9) | 12 046 (7.9) | 2541 (1.7) |
Year of birth, median (IQR) | 152 602 | 1951 (1942-1964) | 1949 (1941-1963) | 1949 (1940-1962) | 1952 (1943-1967) | 1961 (1947-1978) |
BMI at age 7 y, median (IQR), kg/m2 | 143 481 | 14.3 (13.9-14.7) | 15.3 (14.9-15.7) | 16.2 (15.7-16.7) | 17.2 (16.5-17.9) | 19.1 (18.0-20.3) |
Height at age 7 y, median (IQR), m | 143 481 | 1.21 (1.18-1.25) | 1.22 (1.19-1.25) | 1.23 (1.20-1.27) | 1.25 (1.22-1.29) | 1.27 (1.24-1.31) |
Obesity-related cancer, No. (%) | 7261 (4.8) | 1530 (4.3) | 3283 (5.1) | 1865 (4.9) | 510 (4.2) | 73 (2.9) |
Type 2 diabetes, No. (%) | 17 546 (11.5) | 3490 (9.9) | 7002 (10.8) | 4670 (12.3) | 1929 (16.0) | 455 (17.9) |
For the characteristics of individuals in each of the childhood BMI trajectories, individuals were assigned to the trajectory with the highest posterior probability (modal assignment). BMI = body mass index; IQR = interquartile range.
Pre- and postmenopausal breast cancers were defined based on age at diagnosis as younger than age 55 years or age 55 years and older, respectively.