Skip to main content
. 2023 Jan 1;19(2):362–376. doi: 10.7150/ijbs.69784

Figure 5.

Figure 5

YBX1 rescued the FCN3-induced tumor inhibition. (A) Apoptosis rate of HCCLM3 cells transfected FCN3 and YBX1 by flow cytometry. (B) Colony formation assay of HCCLM3 cells was performed to examine the effect on cell proliferation. (C) EdU incorporation assay of HCCLM3 cells transfected FCN3 and YBX1. (D) Relative SBDS mRNA expression in HCCLM3 cells co-transfected with FCN3 and YBX1. (E) Effect of FCN3 and YBX1 overexpression on SBDS and p53-mediated proteins levels. (F) Ribosome profiles at 260nm absorbance in HCCLM3 cells overexpressing FCN3 and YBX1. The location of 40S, 60S and 80S were indicated by arrows. Histograms represent the mean±SD of three independent experiments. *P<0.05, **P<0.01, ***P<0.001.