Table 4:

Association of Past-30-day Cannabis Vaping with Asthma and Other Respiratory Symptoms Among Never Combustible Cigarette Smokers (BRFSS 2017–2019)

	Odds Ratio (95% Confidence Intervals)
	ASTHMA			RESPIRATORY SYMPTOMS*
	Model 1	Model 2	Model 3	Model 1	Model 2	Model 3
Entire Sample	(N=87,483)	(N=86,326)	(N=73,674)	(N=19,345)	(N=19,103)	(N=12,945)
Non-cannabis users (n=87,369)	1.00 (ref)	1.00 (ref)	1.00 (ref)	1.00 (ref)	1.00 (ref)	1.00 (ref)
Cannabis vapers(n=589)	0.91 (0.58–1.42)	0.94 (0.60–1.47)	1.03 (0.64–1.64)	0.88 (0.38–2.01)	1.05 (0.46–2.40)	1.08 (0.44–2.63)
Less frequent (n=448)	0.78(0.44–1.38)	0.81 (0.46–1.43)	0.87(0.48–1.57)	0.95(0.34–2.65)	1.11 (0.39–3.14)	1.00 (0.31–3.21)
More frequent (n=141)	1.25 (0.61–2.57)	1.31 (0.64–2.70)	1.49(0.69–3.20)	0.73(0.23–2.34)	0.92 (0.29–2.91)	1.25 (0.42–3.73)
Excluding persons with COPD	(N=84,409)	(N=83,272)	(N=71,016)	(N=18,692)	(N=18,456)	(N=12,446)
Non-cannabis users (n=84,219)	1.00 (ref)	1.00 (ref)	1.00 (ref)	1.00 (ref)	1.00 (ref)	1.00 (ref)
Cannabis vapers (n=576)	1.01 (0.63–1.61)	0.97 (0.61–1.55)	1.03 (0.63–1.67)	0.96 (0.42–2.19)	1.11 (0.48–2.52)	1.13 (0.46–2.73)
Less frequent (n=440)	0.92 (0.51–1.63)	0.88 (0.50–1.57)	0.92 (0.51–1.67)	1.03 (0.37–2.90)	1.17 (0.41–3.31)	1.06 (0.33–3.38)
More frequent (n=136)	1.28 (0.58–2.81)	1.24 (0.56–2.75)	1.37 (0.60–3.13)	0.79 (0.25–2.56)	0.96 (0.30–3.07)	1.28 (0.42–3.84)

^*Composite of cough, phlegm production, or shortness of breath

Model 1: Unadjusted

Model 2: Age-adjusted

Model 3: Model 2 + sex, race, education, income, body mass index

COPD: Chronic Obstructive Pulmonary Disease