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. 2023 Jan 10;21:4. doi: 10.1186/s12959-022-00448-1

Fig. 3.

Fig. 3

Effects of treatment with recombinant or plasma-derived VWF on PFA COL/ADP closure time of samples from patients with VWD. The closure time was analyzed in-vitro on buffered citrate whole blood from three VWD patients spiked with rVWF or pVWF using the PFA-200 analyzer. If the time until hemostasis was longer than exactly quantifiable by the instrument, the highest value presented by the instrument was chosen for analysis. Data are presented as mean ± SEM. Data were analyzed using unpaired ANOVA. *p<0.05, **p<0.01, ***p<0.001