Table 3.

Regression results for cerebrovascular outcomes

	MCAv	CVCi	PI
Statin	3.88 [0.04–7.71] (0.047)	0.04 [0.002–0.09] (0.04)	− 0.09 [− 0.16 to − 0.03] (< 0.01)
Age	–	–	0.02 [0.01–0.02] (< 0.0001)
Female	6.83 [2.79–10.86] (< 0.01)	0.08 [0.03–0.12] (< 0.001)	–
Beta-blockers	− 4.69 [− 9.44 to 0.06] (0.05)	− 0.05 [− 0.10 to 0.005] (0.07)	–
LDL-C	0.05 [− 0.01 to 0.11] (0.10)	0.0005 [− 0.0001 to 0.011] (0.13)	− 0.001 [− 0.002 to − 0.000002] (0.049)
HDL-C	0.10 [− 0.0004 to 0.21] (0.05)	0.001 [− 0.00002 to 0.002] (0.05)	–
Heart rate	0.24 [0.03–0.46] (0.03)	0.003 [0.0004–0.01] (0.02)	0.004 [0.0002–0.007] (0.04)
Mean arterial pressure	–	− 0.006 [− 0.008 to − 0.004] (< 0.001)	–
End-tidal CO2	0.39 [− 0.05 to 0.84] (0.08)	0.004 [− 0.008 to 0.009] (0.10)	–
Intercept	8.60 [− 12.89 to 30.09] (0.43)	0.63 [0.32–0.94] (< 0.001)	− 0.37 [− 0.77 to 0.02] (0.06)
R-squared	0.17	0.29	0.29
Adjusted R-squared	0.14	0.27	0.28
Residual Std. error	12.34	0.13	0.21
F statistic	5.90 df = 7; 200 (< 0.001)	10.33 df = 8; 199 (< 0.001)	20.74 df = 4; 203 (< 0.001)

Bold indicates significance at p < 0.05

For each variable the primary number is β-weight. A dash (−) indicates the variable dropped during the AIC model selection. 95% confidence intervals are reported in brackets. p-values are reported in parentheses

CVCi cerebrovascular conductance index, HDL-C high-density lipoprotein, LDL-C low-density lipoprotein, MCAv, middle cerebral blood flow velocity, PI pulsatility index