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. 2023 Jan 10;15:2. doi: 10.1186/s13073-022-01145-4

Fig. 5.

Fig. 5

Immunofluorescence staining confirms the activation of MRTFB in mesangial cells during early DN. Immunofluorescence staining of the human kidney samples (ctrl: n = 2, DN: n = 5). Representative images showing the expression and localization of MRTFA and MRTFB in control and DN glomeruli. Glomerular endothelial cells were labeled by CD34, podocytes were labeled by NPHS1 (Nephrin), and nuclei were counterstained with HOECHST. Arrows indicate mesangial cells, which were negative for CD34 and NPHS1