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Immunofluorescence was used to detect the localization of AT protein in HEK293T cells carrying unloaded (Control), wild-type (SERPINC1-WT), Asn460Thrfs*20 mutant (SERPINC1-c.1377delC), and Arg229* mutant (SERPINC1-685C > T). Following SERPINC1 (c.1377del) and SERPINC1 (c.685C-T) mutation, AT protein expression level was attenuated, and the proteins were localized in the cytoplasm
