Fig. 4.

Network analysis showing the patterns of co-occurrence among ARGs, MGEs and bacterial genera. The nodes were colored according to ARG types, MGEs and bacteria. The size of each node was weighted according to the degree. A connection stands for a strong (Spearman's correlation coefficient ρ > 0.8) and significant (adj. P < 0.01) correlation. The green lines indicate co-occurrence (positive) and yellow lines for mutualistic exclusion (negative). MLSB, macrolide-lincosamide-streptogramin B. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)