Table 1.
Technique | Advantages | Drawbacks | References |
---|---|---|---|
Inkjet based | • Low cost • High cell viability (75% – 90%) • Fine printing resolution (~30 μm) • Rapid printing speed (up to 10,000 droplets per second) |
• Low cell density (<106 cells mL-1) • Low-viscosity bioinks (~3 – 12 mPa·s) • Risk of nozzle clogging |
[45,154-157] |
| |||
Microextrusion | • High cell density (~108 cells mL-1, e.g., cell spheroids) • High viscosity bioinks (30 mPa·s-6×107 mPa·s×107 mPa·s) • Medium cell viability (40% – 95%) |
• Low resolution (~100 μm) • Slow printing speed (~10 – 50 μm s-1) • High shear stress • Nozzle clogging |
[158-162] |
| |||
Light assisted | • Ultrafine printing resolution • High cell viability (>95%) • High cell density (108 cells mL-1) • Low-viscosity cell suspensions (1 – 300 mPa·s), • Free from nozzle clogging |
• High cost • Post-printing cell damage • Difficulty in assembling multiple types of bioinks |
[159,163,164] |