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. 2022 Nov 9;9(1):638. doi: 10.18063/ijb.v9i1.638

Table 1.

Comparison of performances of commonly used 3D bioprinting techniques.

Technique Advantages Drawbacks References
Inkjet based • Low cost
• High cell viability (75% – 90%)
• Fine printing resolution (~30 μm)
• Rapid printing speed (up to 10,000 droplets per second)
• Low cell density (<106 cells mL-1)
• Low-viscosity bioinks (~3 – 12 mPa·s)
• Risk of nozzle clogging
[45,154-157]

Microextrusion • High cell density (~108 cells mL-1, e.g., cell spheroids)
• High viscosity bioinks (30 mPa·s-6×107 mPa·s×107 mPa·s)
• Medium cell viability (40% – 95%)
• Low resolution (~100 μm)
• Slow printing speed (~10 – 50 μm s-1)
• High shear stress
• Nozzle clogging
[158-162]

Light assisted • Ultrafine printing resolution
• High cell viability (>95%)
• High cell density (108 cells mL-1)
• Low-viscosity cell suspensions (1 – 300 mPa·s),
• Free from nozzle clogging
• High cost
• Post-printing cell damage
• Difficulty in assembling multiple types of bioinks
[159,163,164]