Table 3.
Overview of Clinical Effectiveness at Month 12 – Retrospective Studies
| Intervention | IOP Measurement | Use of IOP-Lowering Medication | ||||
|---|---|---|---|---|---|---|
| Post-Correction value (mmHg), Mean (SD), [SE] | Absolute Change from Baseline (mmHg), Mean (SD) | % Change from Baseline, Mean (SD) | No. of Post-Operative Medications, Mean (SD), [SE] | Absolute Change from Baseline, Mean (SD) | % Change from Baseline, Mean [SE] | |
| OMNI (overall cohort)72,80,89 | From 13.6 (2.3) to 16.5 (3.4) | −6.9 | From −29 to −41 | From 0.2 (0.6) to 1.9 (1.4) | From −1.9 (1.1) to −1.2 | −89 |
| OMNI (standalone surgery)17,72,80,89,90 | From 14.5 (3.6) to 15.6 (3.6) | From −14.3 (6.9) to −6.5 | From −39.8 to −19.6 (19.2) | From 0.4 (0.6) to 2.0 (1.4) | From −2.2 (1.8) to −0.73 | −70.6 (48.3) |
| OMNI (combined with cataract surgery)70,72,80,89 | From 14.1 (3.3) to 14.6 (2.6) | From −7.6 to −7.45 | From −32.4 to −12.0 (22.7) | From 0.1 (0.5) to 1.9 (1.4) | From −1.6 to −0.45 | NR |
| iStent/iStent inject60,62,63,67,69,74,76,78,79,84,86,91 | From 11.4 (2.6) to 16.34 (3.78) | NR | From −34 to −11 | From 0.36 (0.78) to 1.69 (1.28) | NR | From −75 to −70.3 |
| Hydrus78 | 12.5 | NR | NR | NR | NR | NR |
| Trabeculotomy (GATT, KDB)76 | 15.0 (4.0) | NR | −12.6 | 1.6 (1.3) | NR | NR |
| iTrack (overall cohort)26 | 14.42 (2.2) | NR | NR | 0.26 (0.56) | NR | −82.4 |
| iTrack (standalone surgery)26 | 15.6 (3.1) | NR | NR | 0.53 (0.14) | NR | −64.8 |
| iTrack (combined with cataract surgery)26 | 14.3 (3.8) | NR | NR | 0.16 (0.11) | NR | −88.5 |
Notes: only interventions with at least one 12-month follow-up retrospective study were included in the table.
Abbreviations: GATT, gonioscopy-assisted transluminal trabeculotomy; IOP, intraocular pressure; KDB, Kahook Dual Blade; NR, not reported; SD, standard deviation; SE, standard error; SLT, selective laser trabeculoplasty.