Table 6.

Mediation analysis of ADI on associations observed between Black or White race with LOS > 3 days and nonhome discharge in patients who underwent TKA

Association	Estimate (95% CI)	p value	% mediation
LOS > 3 days
Mediation (indirect)	-0.021 (-0.035 to -0.007)	0.004	19%
Direct	-0.088 (-0.126 to -0.049)	< 0.001	81%
Total	-0.109 (-0.146 to -0.072)	< 0.001	100%
Nonhome discharge
Mediator (indirect)	0.029 (-0.016 to 0.04)	< 0.001	38%
Direct	0.046 (0.014 to 0.078)	0.006	62%
Total	0.075 (0.042 to 0.106)	< 0.001	100%

Mediation analysis explored the degree to which the observed relationship between race (independent variable) and LOS 3 or more days/nonhome discharge (dependent variables) was completely or partially explained by ADI (mediator). The estimates from mediation analysis represent the proportion of the total effect on the dependent variables that may be attributed to the independent variable and the mediator. The mediation (indirect) effect divided by the total effect was used to calculate the percent mediation for each outcome.