Table 2.
Regions showing significant negative associations between fear contrasts and PCL-R Total scores during the affective perspective-taking task in whole-brain analyses (uncorrected p = .002; pFWE < 0.05).
| Contrast | Brain Region | L/R | MNI Peak Coordinates(x, y, z) | Size (Voxels) | Peakt-value |
|---|---|---|---|---|---|
| Fear > Neutral | Superior Occipital Cortex | L | −37, −78, 31 | 36 | −3.87 |
| Superior Parietal Lobule | L | −30, −64, 52 | 21 | −3.82 | |
| Brainstem | R | 9, −19, −15 | 20 | −4.01 | |
| Precuneus | R | 5, −50, 56 | 18 | −3.78 | |
| Anterior Insula/ | L | −30, 13, −15 | 16 | −3.87 | |
| Posterior Orbitofrontal Cortex | |||||
| Fear > (Anger + Happiness + Sadness) | Superior Occipital Cortex | R | 30, −75, 28 | 21 | −4.20 |
| Precentral Gyrus | L | −37, −8, 45 | 18 | −4.38 | |
| Postcentral Gyrus | R | 33, −43, 52 | 17 | −4.29 | |
| Precuneus | R | 9, −64, 52 | 17 | −3.69 | |
| Superior Occipital Cortex | R | 30, −85, 14 | 16 | −3.60 | |
| Fusiform Gyrus | L | −26, −36, −11 | 12 | −3.33 | |
| Postcentral Gyrus | L | −40, −33, 52 | 12 | −3.39 |
All models controlled for age, race/ethnicity, substance abuse and IQ.
In the Fear > Neutral contrast, all regions were additionally significant at a Bonferroni-corrected level of PFWE < 0.01 (cluster size > 14, uncorrected p = .002).