FIG. 5.

Median (D50) particle size and morphology for spray-dried particle groups. (a–c) An increase in the Ohnesorge number resulted in an enlarged aggregated particle size in the nonvolatile ratio and polymer coating ratio control group. Silane treatment did not have an effect on the Ohnesorge number, but still caused a significant difference in particle size (n > 80; median ± SE; ****p < 0.0001). (d–f) The aspect ratio was significantly changed by the Ohnesorge number in the nonvolatile ratio and polymer coating ratio control group (n > 80; median ± SE; **p < 0.01; ***p < 0.001). No significant difference in aspect ratio was observed between the silane treatment conditions and the control group. SE, standard error. Color images are available online.