Table 2.
Ovarian stimulation and oocyte yield parameters
| Parameter | Pre-vaccination (n = 115)a | 95% CI | Post-vaccination (n = 115)a | 95% CI | Difference | 95% CIb | P-value | |
|---|---|---|---|---|---|---|---|---|
| Duration of stimulation (days) | 9.51 | 9.2–9.8 | 10.31 | 10–11 | –0.80 | –1.13 to –0.48 | <0.001c | |
| Dose of gonadotrophins (IU) | 2235.54 | 2122–2349 | 2453.48 | 2,317–,590 | –218 | –305.27 to –130.60 | <0.001b | |
| Oocytes retrieved (n) | 15.38 | 14–17 | 16.62 | 15–18 | –1.24 | –2.34 to –0.14 | 0.028b | |
| Metaphase II oocytes (n) | 12.61 | 12–14 | 13.01 | 12–14 | –0.40 | –1.32 to 0.52 | 0.39b | |
| Mature/total oocyte ratio | 0.83 | 0.80–0.85 | 0.77 | 0.74–0.80 | 0.05 | 0.02 to 0.09 | 0.019c | |
The same women were included in the pre- and post-vaccination groups.
a
Data are means.
b
Paired t-test.
c
Wilcoxon signed-rank test.