Table 1:
Demographic and clinical features of the cohort, with comparison of features between participants within the Mayo Clinic Study of Aging who underwent formal behavioural audiometric testing versus those who did not
| Underwent formal audiometric testing |
p value | ||
|---|---|---|---|
| No (N=4297) | Yes (N=1200; study cohort) | ||
|
| |||
| Demographic and clinical features | |||
| Age, years | 72 (10) | 76 (9) | <0·0001 |
| Sex | .. | .. | 0·31 |
| Female | 2102 (49%) | 607 (51%) | .. |
| Male | 2195 (51%) | 593 (49%) | .. |
| White race (N=4277; N=1196) | 4206 (98%) | 1177 (98%) | 0·86 |
| Non-Hispanic or Latino ethnicity (N=4273; N=1194) | 4254 (>99%) | 1193 (>99%) | 0·10 |
| Years of education (N=4292; N=1198) | .. | .. | <0·0001 |
| ≤12 | 1506 (35%) | 342 (29%) | .. |
| 13–16 | 1976 (46%) | 544 (45%) | .. |
| >16 | 810 (19%) | 312 (26%) | .. |
| Smoking status (N=4295; N=1200) | .. | .. | 0·18 |
| Never | 2310 (54%) | 619 (52%) | .. |
| Current or former | 1985 (46%) | 581 (48%) | .. |
| Comorbidities (N=4275; N=1199) | |||
| Diabetes | 748 (18%) | 220 (18%) | 0·49 |
| Hypertension | 2850 (67%) | 868 (72%) | 0·0002 |
| Stroke | 180 (4%) | 63 (5%) | 0·12 |
| Heart disease | 1458 (34%) | 504 (42%) | <0·0001 |
| Beck Depression Inventory II score ≥13 (N=4218; N=1169) | 316 (7%) | 100 (9%) | 0·23 |
| APOE ε4 carriership (N=3974; N=1148) | 1110 (28%) | 285 (25%) | 0·04 |
| Hearing rehabilitation | 399 (9%) | 492 (41%) | <0·0001 |
| Exposures | |||
| PTA in dB HL | .. | 32 (16) | .. |
| Hearing severity classification | |||
| Normal hearing | .. | 437 (36%) | .. |
| Mild hearing loss | .. | 383 (32%) | .. |
| Moderate hearing loss | .. | 363 (30%) | .. |
| Severe or profound hearing loss | .. | 17 (1%) | .. |
| WRS in % (N=1173) | .. | 91 (14) | .. |
| WRS <90% (N=1173) | .. | 271 (23%) | .. |
| WRS <100% (N=1173) | .. | 545 (46%) | .. |
| Informant-based hearing difficulties (N=1177) | .. | 388 (33%) | .. |
| Cognitive status at enrolment | |||
| Unimpaired | .. | 1041 (87%) | .. |
| Mild cognitive impairment | .. | 159 (13%) | .. |
| Z-scores at enrolment | |||
| Memory (N=1177) | .. | −0·22 (1·13) | .. |
| Attention/executive function (N=1145) | .. | −0·16 (1·11) | .. |
| Language (N=1150) | .. | −0·18 (1·13) | .. |
| Visuospatial skills (N=1141) | .. | −0·12 (1·06) | .. |
| Global cognition (N=1111) | .. | −0·20 (1·13) | .. |
Data are mean (SD) or n (%). Sample sizes for features with missing data are indicated in parentheses. dB HL=decibels hearing level. APOE=apolipoprotein E. PTA=pure-tone average. WRS=word recognition score.