Fig. 1.

Labeling process (A) the manually drawn region of interest (ROI) 1 (red-dashed box) around the cervical vertebrae is labeled with the patient's hand-wrist bone age. (B) The cervical vertebrae (blue color) are labeled as the ground truth on each lateral cephalogram. ROI 2 from the ROI extraction process is labeled with the same patient's hand-wrist bone age. (For interpretation of the references to color/color in this figure legend, the reader is referred to the Web version of this article.)