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. 2022 Dec 25;10(6):366–376.

Figure 2.

Figure 2

Structure of the androgen receptor (AR). The AR contains a N-terminal domain (NTD), DNA binding domain (DBD), hinge region (H), and ligand binding domain (LBD). The nuclear degradation signal (NDS) regulates AR nuclear proteasomal degradation in a hormone-dependent manner. K311, K845, and K847 are known ubiquitination sites on AR.