Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Dec 28;13:1088024. doi: 10.3389/fimmu.2022.1088024

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2022 Oravecz, Romero, Tóth, Kapitány, Posta, Gallo, Rossi, Tarca, Erez, Papp, Matkó, Than and Balogh

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

The effects of placental galectins on leukocyte functions. Gal-13 and gal-14 bind to the surface of immune cell populations where they activate Erk1/2, p38 MAPK, and NF-κB signaling pathways. These signaling effects of placenta-specific galectins increase the viability of leukocytes, decrease the apoptosis of immune cells without influencing the proliferation of cells, and induce the production of IL-8, IL-10, and IFN-γ in a different manner. Erk1/2, extracellular signal-regulated kinase 1/2; IFN, interferon; IL, interleukin; MAPK, mitogen-activated protein kinase; NF-κB, nuclear factor kappa B.