TABLE 2.

Scoring of macroscopic lung lesions in immunized mice following challenge with FD 4 P. aeruginosa in a chronic pulmonary infection model

Immunization group	No. of mice scored asa:					No. of mice with severe (≥2+) lung lesions/total no. of mice (%)
	0	1+	2+	3+	4+
Vector control	9	1	6	12	14	32/42 (76.2)
DNA-protein F	18	7	5	9	5	19/44 (43.2)

^aLesions were scored as follows: 0, absence of any macroscopic lesion; 1+, presence of one or two small lesions not exceeding 1 mm in diameter; 2+, presence of three or more small lesions not exceeding 1 mm in diameter; 3+, presence of a medium lesion 2 to 5 mm in diameter; 4+, presence of a large lesion exceeding 5 mm in diameter. The P value was 0.002 as determined by Fisher's exact test.