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. 2023 Jan 11;15:12. doi: 10.1186/s13195-022-01123-3

Table 4.

Results of the mixed models’ intention to treat analyses on secondary outcome measures of physical and mental health

Intervention group
N = 69
Control group
N = 33
Model A
N = 102
Model B
N = 96
Mean (sd) Mean (sd) B (95% CI) P value d B (95% CI) P value d
ADL limitations
 Baseline 0.23 (0.86) 0.33 (0.69)
 9 months 0.23 (0.73) 0.42 (0.71)  − 0.10 (− 0.19 to − 0.004) .04 .12  − 0.11 (− 0.21 to − 0.01) .03 .14
Experienced frailty
 Baseline 0.11 (0.07) 0.12 (0.07)
 9 months 0.11 (0.06) 0.11 (0.07) 0.00 (− 0.01 to 0.01) .46 0 0.00 (− 0.00 to 0.01) .33 0
Mental health
 Baseline 81.67 (11.00) 79.96 (13.94)
 9 months 81.07 (12.85) 83.52 (11.61)  − 2.50 (− 4.51 to − 0.50) .02 .21  − 2.48 (− 4.62 to − 0.34) .02 .21

Intervention group

N = 39

Control group

N = 23

Model A

N = 62

Model B

N = 56

Mean (sd) Mean (sd) B (95% CI) P value d B (95% CI) P value d
Depressive symptoms
 Baseline 8.92 (6.05) 8.35 (6.67)
 9 months 7.64 (5.72) 8.30 (7.35)  − 0.67 (− 1.95 to 0.60) .30 .11  − 0.86 (− 2.27 to 0.55) .23 .14

Model A: adjusted for y at baseline, age, and sex. Model B: adjusted for y at baseline, age, sex, education, and ApoE-ε4 carrier status. PA Physical activity as measured in daily number of steps taken, ADL Activities of daily living, IGF-I Insulin-like growth factor 1, HDL High-density lipoprotein, d Cohen’s d