Table 7.
Results of the mixed models analyses investigating the effect of a >= 35% increase in physical activity on secondary outcome measures of physical and mental health
> = 35% increase PA T2 N = 35 |
< 35% increase PA T2 N = 45 |
Model A N = 80 |
Model B N = 75 |
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Mean (sd) | Mean (sd) | B (95% CI) | P value | d | B (95% CI) | P value | d | |
ADL limitations | ||||||||
Baseline | 0.17 (0.45) | 0.22 (0.60) | ||||||
9 months | 0.14 (0.36) | 0.33 (0.67) | − 0.08 (− 0.19 to 0.02) | .12 | .15 | − 0.13 (− 0.24 to − 0.02) | .02 | .24 |
Experienced frailty | ||||||||
Baseline | 0.10 (0.05) | 0.12 (0.07) | ||||||
9 months | 0.10 (0.05) | 0.12 (0.07) | − 0.01 (− 0.02 to 0.003) | .15 | .16 | − 0.01 (− 0.02 to 0.003) | .18 | .16 |
Mental health | ||||||||
Baseline | 82.81 (10.73) | 79.53 (13.84) | ||||||
9 months | 83.99 (10.12) | 82.81 (10.73) | 0.79 (− 1.59 to 3.17) | .52 | .06 | 0.79 (− 1.78 to 3.37) | .55 | .06 |
> = 35% increase PA T2 N = 26 |
< 35% increase PA T2 N = 29 |
Model A N = 55 |
Model B N = 50 |
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Mean (sd) | Mean (sd) | B (95% CI) | P value | d | B (95% CI) | P value | d | |
Depressive symptoms | ||||||||
Baseline | 7.04 (5.29) | 9.86 (6.95) | ||||||
9 months | 6.08 (4.83) | 9.00 (7.33) | − 0.36 (− 1.76 to 1.04) | .61 | .06 | − 0.86 (− 2.40 to 0.68) | .28 | .14 |
Model A: adjusted for y at baseline, age, and sex. Model B: adjusted for y at baseline, age, sex, education, and ApoE-ε4 carrier status. PA Physical activity as measured in daily number of steps taken, ADL Activities of daily living, IGF-I Insulin-like growth factor 1, HDL High-density lipoprotein, d Cohen’s d