Table 8.
Results of the mixed models analyses investigating the effect of a >= 35% increase in physical activity on serum concentrations 6 months after the start of the intervention (T1)
| Outcome |
> = 35% increase PA T2 N = 35 |
< 35% increase PA T2 N = 38 |
Model A N = 71 |
Model B N = 71 |
||||
|---|---|---|---|---|---|---|---|---|
| Serum concentrations | Mean (sd) | Mean (sd) | B (95% CI) | P value | d | B (95% CI) | P value | d |
| IGF-I | ||||||||
| Baseline | 14.55 (3.79) | 13.87 (4.43) | ||||||
| 6 months | 15.27 (3.80) | 14.55 (3.79) | − 0.25 (− 0.85 to 0.35) | .41a | .06 | − 0.31 (− 0.98 to 0.34) | .35a | .07 |
| Insulin | ||||||||
| Baseline | 53.84 (39.21) | 51.93 (36.92) | ||||||
| 6 months | 46.36 (46.01) | 44.89 (22.09) | 1.66 (− 3.74 to 7.05) | .55 | .04 | 1.57 (− 4.33 to 7.48) | .60 | .04 |
| Total cholesterol | ||||||||
| Baseline | 5.47 (1.25) | 5.19 (1.15) | ||||||
| 6 months | 5.58 (1.12) | 5.18 (1.08) | 0.02 (− 0.10 to 0.14) | .72 | .02 | 0.03 (− 0.10 to 0.16) | .65 | .03 |
| HDL-cholesterol | ||||||||
| Baseline | 1.41 (0.44) | 1.45 (0.39) | ||||||
| 6 months | 1.50 (0.44) | 1.45 (0.39) | 0.02 (− 0.02 to 0.06) | .38 | .05 | 0.02 (− 0.02 to 0.07) | .34 | .05 |
| Triglycerides | ||||||||
| Baseline | 1.43 (0.66) | 1.62 (1.25) | ||||||
| 6 months | 1.40 (0.74) | 1.63 (0.96) | 0.001 (− 0.13 to 0.13) | .99 | 0 | − 0.02 (− 0.16 to 0.12) | .76 | .02 |
aEffect moderation by sex observed. Model A: adjusted for y at baseline, age, and sex. Model B: adjusted for y at baseline, age, sex, education, and ApoE-ε4 carrier status
PA Physical activity as measured in daily number of steps taken, ADL Activities of daily living, IGF-I Insulin-like growth factor 1, HDL High-density lipoprotein, d Cohen’s d