Table 1.

Main clinical characteristics of the ECD population (n = 32)

	n (%)
BRAF V600E mutation	20 (62.5)
Age at first symptoms (mean[SD])	49.6 [14.2]
Current treatment
Steroid	6 (18.8)
Interferon alpha	2 (6.3)
Vemurafenib	12 (37.5)
Cobimetinib	4 (12.5)
Others	5 (15.6)
Past treatment
Steroid	13 (40.6)
Interferon alpha	24 (75)
Vemurafenib	12 (37.5)
Cobimetinib	7 (21.9)
Others	13 (40.6)
Cerebral MRI patterns*
MRI considered as normal	8 (25)
Tumoral patterns	19 (59.4)
Pseudo-degenerative patterns	15 (46.9)
Vascular patterns	7 (21.9)

ECD Erdheim-Chester disease

*MRI patterns was described on the basis of prior publications (see reference Cohen-Aubart et al. [7])